Mounjaro vs Wegovy: Which One Is Right for You?

Mounjaro and Wegovy are both prescription weight-management medicines taken as a once-weekly injection. They work in a similar way, but they are not the same. Your practitioner decides which one, if either, suits you.

Our top pickMyShape

9.7/10
our rating
$197first month

Then from $417/month, the same as Lean and Prime. Australian-registered practitioners, Australian pharmacy, monthly billing.

Lowest first month of the 5 we compared

Check eligibility at MyShape$197 first month if prescribed. Free online assessment.

Free online assessment. An Australian-registered practitioner decides if it suits you.

Side-by-side comparison

MounjaroWegovy
Active ingredientTirzepatideSemaglutide
How it worksActs on two appetite hormones (GIP and GLP-1)Acts on one appetite hormone (GLP-1)
How you take itOnce-weekly injection penOnce-weekly injection pen
Average weight loss in the main trialAbout 21% at the highest dose over 72 weeks (SURMOUNT-1)About 15% over 68 weeks (STEP 1)
Online price (first month)From $197 (MyShape)From $297
Ongoing priceFrom $417/monthFrom $397/month

Trial results are averages from clinical trials alongside diet and exercise. Individual results vary.

Which is better?

In the main clinical trials, average weight loss was higher with Mounjaro. But the right medicine depends on your health, your other medicines, how you tolerate side effects and your budget. Both can cause nausea and other stomach side effects, especially when the dose goes up. Your practitioner will talk through these with you.

Can I choose which one I get?

You can tell the practitioner what you would prefer, but they make the final decision. Online providers like MyShape, Lean and Prime offer both.

Sources: SURMOUNT-1 (NEJM, 2022), STEP 1 (NEJM, 2021). Updated .

MyShape

Start for $197 instead of $317

Same $417/month as Lean and Prime after that, with an Australian-registered practitioner and an Australian pharmacy.

Check eligibility at MyShape$197 first month if prescribed. Free online assessment.
MyShape
MyShape: $197 first monthThen from $417/mo, same as Lean and Prime
Check eligibility